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近年有报道脐血乳酸盐和次黄嘌呤水平升高是新生儿急性窒息的指标。另有报告胎儿出生前在宫内长时间的应激反应可使红细胞生成素水平升高。为确定足月分娩新生儿的乳酸盐、次黄嘌呤和红细胞生成素水平与出生时羊水粪染的相关性,将56例正常妇女孕足月临产时根据自然或人工破膜后吸取的羊水情况分成两组。羊水清亮28例,粪染28例,粪染程度根据离心后胎粪的百分体积分为三度:胎粪≤26为稀薄11例;≥31为中等粘稠16例;≥35为粘稠2例。胎儿均被电子胎心监护仪连续监护。取脐动脉血测pH值,取脐动、静脉混合血测定乳酸盐、次黄嘌呤和红细胞生成素水平。 结果:两组产妇年龄、产次、产程、分娩方式、脐血pH、5分钟Apgar评分和出生体重无差异,胎心率监护无胎儿窘迫,羊水粪染组新生儿平均孕龄较长。粪染组与对照组的乳酸盐水平分别为30.5±
In recent years, umbilical cord blood lactate and hypoxanthine levels have been reported as an indicator of acute neonatal asphyxia. Another report before the fetus in the palace a long time of stress response can make erythropoietin levels. To determine the full-term neonatal delivery of lactate, hypoxanthine and erythropoietin levels and the incidence of amniotic fluid at birth associated with the dye, 56 normal women during full term pregnancy, according to natural or artificial rupture of the amniotic fluid The situation is divided into two groups. Amniotic fluid clear 28 cases, 28 cases of fecal infection, fecal contamination according to the percentage of meconium after centrifugation is divided into three degrees: meconium ≤ 26 for the thin 11 cases; ≥ 31 for the middle of viscous in 16 cases; ≥ 35 for the viscous 2 cases. Fetal fetal heart rate monitor were continuous monitoring. Take umbilical artery blood to measure the pH value, take umbilical artery and vein mixed blood to measure lactate, hypoxanthine and erythropoietin levels. Results: There was no difference between the two groups in terms of maternal age, parity, labor course, mode of delivery, umbilical cord blood pH, 5-minute Apgar score and birth weight. Fetal heart rate monitoring had no fetal distress. The levels of lactate in fecal and control groups were 30.5 ±