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作者用12周龄的白色新西兰种家兔进行试验,以检验肠道淋巴组织在口服免疫过程中的致敏情况。家兔连续饮用含0.1％牛血清白蛋白(BSA)的水,日饮量约为200～600ml。另一组于脚掌注射2mg不含佐剂的BSA生理盐水液作为比较。所有家兔免疫前血清中均不含抗BSA抗体。
The authors used 12-week-old white New Zealand rabbits to test the sensitization of gut lymphoid tissues during oral immunization. Rabbits continuously drink water containing 0.1% bovine serum albumin (BSA), daily drinking capacity of about 200 ~ 600ml. The other group received 2 mg of adjuvant-free BSA saline in the soles of feet for comparison. All rabbits did not contain anti-BSA antibody in pre-immune serum.