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患儿,男,13岁,因患结核性胸膜炎于1988年10月始用异烟肼,每日300mg口服,链霉素每日0.75g肌注;利福平每日0.3g口服.两个月后停链霉素,3个月后停利福平,异烟肼以原量继续口服.5个月时患者自述双侧乳房肿痛,未引起家长注意,此后又持续用药半个月,患者双侧乳房增大,并疼痛加剧前来就诊.查体:双侧乳房对称性胀大约8×8cm,乳房皮肤表面光亮,不红。乳晕不明显,乳头无分泌物.明显触痛,中等硬.无结节,无波动感。未听到杂音.肝功正常. 停药1个月后双乳房胀痛明显减轻,但乳房无明显缩小,停药4个月后,双乳房明显缩小,亦无任何压痛,半年后双乳房恢复如初.
Children, male, 13 years old, suffering from tuberculous pleurisy in the beginning of October 1988 with isoniazid, 300mg daily oral, streptomycin daily 0.75g intramuscular injection; rifampicin 0.3g daily oral .Two Month after stopping streptomycin, three months after stopping rifampicin, isoniazid in the original amount to continue oral .5 months when the patient reported breast swelling and pain on both sides, did not cause parents to pay attention, then continued medication for half a month, Patients with bilateral breast enlargement and pain come to treatment. Examination: bilateral breast symmetry swollen about 8 × 8cm, breast skin surface bright, not red. Areola is not obvious, the nipple without secretions. Obvious tenderness, moderate hard. No nodules, no fluctuations. No noise, no abnormal noise, normal liver function.After 1 month of withdrawal, the pain in the double breasts was relieved but the breasts did not shrink significantly. After 4 months of withdrawal, the double breasts were significantly reduced and no tenderness was found. As early as.