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妊娠相关蛋白-A是一种高分子量的锌结合金属蛋白酶,是易损斑块新的标志物。PAPP-A检测方便,许多研究者已经证明它在检测易损斑块方面的准确性,并且能够预测预后和指导治疗。现就其生物学特性和临床意义作简要综述。
Pregnancy Associated Protein-A is a high molecular weight zinc-binding metalloproteinase that is a novel marker of vulnerable plaque. PAPP-A is easy to detect, and many researchers have demonstrated its accuracy in detecting vulnerable plaques and can predict prognosis and guide therapy. Now on its biological characteristics and clinical significance of a brief review.