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本文对２４例恶性胸腔积液患者测定胸液的癌胚抗原（ＣＥＡ）、可溶性白细胞介素－２受体（ＳＩＬ－２Ｒ）浓度及核仁组成区嗜银染色（Ａｇ－ＮＯＲ）计数，并以２０例结核性胸膜炎患者做对照研究。结果表明：恶性胸液组ＣＥＡ为４７．３１±２１．３２μｇ／Ｌ，明显大于结核性胸液组（３．５８±３．０７μｇ／Ｌ）（Ｐ＜０．００１）。恶性胸液组Ａｇ－ＮＯＲ计数４．５８±１．１９个／细胞，明显大于结核性胸液组（１．５１±０．４０个／细胞）（Ｐ＜０．０１），而ｓＩＬ－２Ｒ结核组为１０６１．７８±４５５．３０ＫＵ／Ｌ，大于恶性胸液组（４４２．１９±２８３．７７ＫＵ／Ｌ），（Ｐ＜０．０１）。提示三项指标同时检测，综合分析有利于恶性胸液的诊断。
In this paper, 24 cases of malignant pleural effusions were measured in the thoracic fluid for carcinoembryonic antigen (CEA), soluble interleukin-2 receptor (SIL-2R) concentration, and Ag-NOR counts. Twenty patients with tuberculous pleurisy were used as a controlled study. The results showed that the CEA in the malignant effusion group was 47.31±21.32 μg/L, which was significantly higher than that in the tuberculous pleural fluid group (3.58±3.07 μg/L) (P<0.001). The Ag-NOR count in the malignant pleural fluid group was 4.58±1.19 cells/cell, which was significantly greater than that in the tuberculous pleural fluid group (1.51±0.40 cells/cell) (P<0.01), while sIL-2R The tuberculosis group was 1061.78±455.30 KU/L, which was larger than the malignant pleural fluid group (442.19±283.77 KU/L) (P<0.01). It is suggested that the three indicators should be tested at the same time. Comprehensive analysis is helpful to the diagnosis of malignant pleural fluid.