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OPC-13340是一种新型的二氢吡啶钙通道阻滞剂。其化学方程式为3-甲基-2-苯基-(E)-丙烯基-1,4-二氢基-2,6双甲基-4-(3-硝基苯-3,5-二羟基啶。它具有长效降压作用。服药一次可维持20～22小时。本文通过对原发性高血压病人每天日常活动时的动脉内动态血压的检测,观察OPC-13340的降压持续时间及其效果。病人和方法:14例,男9例,女5例。年龄37～58岁(平均59岁),均为原发性高血压,受试前3周停用一切作用于心脏的药物并排除糖尿病,难(?)性心力(?),新(?)心肌梗塞,心律失常,肾功能衰
OPC-13340 is a novel dihydropyridine calcium channel blocker. Its chemical formula is 3-methyl-2-phenyl- (E) -propenyl-1,4-dihydro-2,6-dimethyl-4- Hydroxy pyridine. It has a long-term antihypertensive effect. Taking a drug can be maintained for 20 to 22 hours.This article through the daily activities of essential hypertension in patients with intra-arterial blood pressure test to observe the antihypertensive duration of OPC-13340 And its effect.Patients and methods: 14 cases, 9 males and 5 females.Ages ranging from 37 to 58 years old (average 59 years), all of them were of essential hypertension, all the three weeks before the trial to disable all the role in the heart Drugs and exclude diabetes, difficult (?), (?), New (?) Myocardial infarction, arrhythmia, renal failure