论文部分内容阅读
目的对比观察贝那普利与卡托普利治疗轻、中度高血压患者的临床疗效与安全性。方法将120例高血压患者随机平分为两组,分别给予贝那普利和卡托普利治疗,均加用小剂量氢氯噻嗪,治疗8周,于治疗前及治疗8周末行血压监测,评定各组降压效果。结果贝那普利组患者降压有效率高于卡托普利组,组间比较差异有统计学意义(P<0.05);不良反应发生率两组间差异无统计学意义(P>0.05)。结论贝那普利对轻、中度原发性高血压病有较好的降压效果,联合应用小剂量利尿剂可提高疗效。
Objective To compare the clinical efficacy and safety of benazepril and captopril in patients with mild to moderate hypertension. Methods A total of 120 hypertensive patients were randomly divided into two groups. The patients were treated with benazepril and captopril respectively. All patients were treated with low-dose hydrochlorothiazide for 8 weeks. Blood pressure was monitored before treatment and 8 weeks after treatment. Buck effect. Results The effective rate of antihypertensive treatment in benazepril group was higher than that in captopril group (P <0.05). The incidence of adverse reactions was no significant difference between the two groups (P> 0.05) . Conclusion benazepril has a good antihypertensive effect on mild to moderate essential hypertension, combined with low-dose diuretics can improve the curative effect.