【摘 要】
：
巯甲丙脯酸(captopril,以下间称CPT),1977年由于ondett等到人合成,1978年由Gavras首先用于临床,1979年国内合成此药并用于临床。CPT是血管紧张素转换酶的抑制剂,具有扩张动
【机 构】
：
兰州军区乌鲁木齐总医院预防保健科 830000
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巯甲丙脯酸(captopril,以下间称CPT),1977年由于ondett等到人合成,1978年由Gavras首先用于临床,1979年国内合成此药并用于临床。CPT是血管紧张素转换酶的抑制剂,具有扩张动脉和静脉血管,减轻心脏前后负荷的作用,主要用于治疗高血压病与心力衰竭等。由于CPT的广泛应用,其副作用也日益受到重视,现根据文献作一概述。
Captopril (captopril, hereinafter referred to as CPT), 1977 due to ondett wait until the human synthesis, 1978 first by Gavras for clinical, domestic synthesis of this medicine in 1979 and for clinical use. CPT is an inhibitor of angiotensin-converting enzyme, with the expansion of arteries and veins, reduce the load before and after the role of the heart, mainly for the treatment of hypertension and heart failure. Due to the widespread use of CPT, its side effects have also received increasing attention and are summarized in the literature.
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