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目的探讨支气管镜下钳夹及注入抗结核药物联合雾化吸入对支气管结核的治疗效果。方法选取2010年1月到2014年12月收治的支气管结核患者236例为研究对象进行回顾性分析,根据治疗方法的不同分为观察组(n=114)和对照组(n=122)。两组均进行全身抗结核药物治疗,同时对照组给予雾化吸入治疗,观察组在此基础上联合支气管镜下钳夹及注药治疗。观察其疗效及复发情况。结果观察组114例中显效70例,好转27例,无效17例,总有效率85.09%;对照组122例中显效59例,好转30例,无效33例,总有效率72.95%;观察组总有效率明显高于对照组(χ2=5.199,P<0.05)。停药1年后观察组复发率5.26%(6/114),对照组复发率13.11%(16/122),观察组复发率明显低于对照组(χ2=4.298,P<0.05)。结论在全身抗结核药物治疗基础上,使用支气管镜下注药联合雾化吸入可提高支气管结核的临床疗效,降低复发率。
Objective To investigate the therapeutic effect of bronchoscopic clamp and injection of anti-tuberculosis drugs combined with inhalation on bronchial tuberculosis. Methods A total of 236 patients with bronchial tuberculosis admitted from January 2010 to December 2014 were retrospectively analyzed. According to the different treatment methods, the observation group (n = 114) and the control group (n = 122). Both groups were treated with systemic antituberculotics while the control group was given inhalation therapy. On the basis of this observation, the observation group was treated with bronchoscopy and injection. To observe the efficacy and recurrence. Results The observation group of 114 cases markedly effective in 70 cases, 27 cases improved, 17 cases ineffective, the total effective rate was 85.09%; control group 122 cases markedly effective in 59 cases, improved in 30 cases, ineffective in 33 cases, the total effective rate was 72.95% Effective rate was significantly higher than the control group (χ2 = 5.199, P <0.05). The recurrence rate of observation group was 5.26% (6/114) after one year of treatment, and the recurrence rate was 13.11% (16/122) in control group. The recurrence rate in observation group was significantly lower than that in control group (χ2 = 4.298, P <0.05). Conclusion Based on systemic anti-TB drug therapy, bronchoscopic injection and atomization inhalation can improve the clinical efficacy and reduce the recurrence rate of bronchial tuberculosis.