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本文观察肾移植受者经环孢素A(CsA)治疗后,B细胞、T细胞及其亚群的变化。发现其对B细胞无显著影响,而使T细胞总数及其亚群T—Sens、T—Res均有降低,与原用传统免疫抑制剂比较,T细胞总数的下降更为显著,认为这可能是CsA能较好地抑制排斥反应的原因。
This article investigates the changes of B cells, T cells and their subgroups after renal transplantation recipients receive cyclosporine A (CsA) treatment. It was found that it had no significant effect on B cells, but decreased the total number of T cells and T-Sens and T-Res of its subgroups. Compared with the traditional immunosuppressive agents, the total number of T cells decreased more significantly. Is CsA can better inhibit the rejection reaction.