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对 2 0例非小细胞肺癌病例进行治疗分析 ,探讨化疗致白细胞减少用格拉诺赛特 (G CSF)的时机、剂量、用药时间的长短。总结 2 0例化疗后白细胞减少病例 ,白细胞低于 2 5× 10 9 L时开始应用G CSF ,剂量 5 0~ 2 5 0 μg d ,连续肌肉注射 ,时间 3~ 10d。结果升白细胞作用明显 ,缩短白细胞减少期。化疗结束后 2 4h预防应用G CSF可防止白细胞下降。此药副作用少见 ,可有发热、皮疹、流涕、肌肉酸痛等表现。
A treatment analysis of 20 cases of non-small cell lung cancer was performed to investigate the timing, dose, and duration of administration of Granocell (G CSF) in leukopenia induced by chemotherapy. Summary In 20 cases of neutropenia after chemotherapy, G CSF was started when the number of white blood cells was lower than 25 × 10 9 L. The dose was 50-250 μg d, and continuous intramuscular injection was performed for 3-10 days. As a result, the effect of increasing leukocytes is obvious and the period of leukopenia is shortened. Preventing the application of G CSF 24 h after the end of chemotherapy can prevent leukocyte decline. The side effects of this drug are rare, and there may be fever, rash, runny nose, muscle soreness and other symptoms.