论文部分内容阅读
该研究旨在评估2型糖尿病患者收缩压、舒张压与心血管疾病住院风险的相关性。方法:纳入英国剑桥郡18家医疗机构的2型糖尿病患者4704例,获取其2008-2009年血压资料。主要观察指标为2009-2011年心血管疾病住院情况。采用Cox模型评估每个血压测量组调整后的相对危险度。采用三次样条曲线模型进一步分析血压和住院风险的量效关系。结果:随访时间中位数为2年,研究人员收集到5322例
The aim of the study was to evaluate the association between systolic blood pressure, diastolic blood pressure, and hospitalization for cardiovascular disease in patients with type 2 diabetes. Methods: 4704 patients with type 2 diabetes from 18 medical institutions in Cambridgeshire, UK were enrolled and their blood pressure data were obtained from 2008 to 2009. MAIN OUTCOME MEASURES: Hospitalization of cardiovascular diseases 2009-2011. The Cox model was used to assess the adjusted relative risk for each BP measurement group. A cubic spline curve model was used to further analyze the dose-response relationship between blood pressure and hospitalization risk. Results: The median follow-up time was 2 years and the researchers collected 5322 cases