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应用超微电极技术在体测定骨骼肌细胞膜电位(Skeletal Muscle Cellular Membrane Potential 简称SMCMP)可以直接反映和监测休克状态下细胞膜和细胞功能的改变,但是有关休克时SMCMP下降的机制尚有争议。本实验应用“半浮置”式玻璃超微电极技术在体测定SMCMP的实验方法,同时观测家兔失血性休克不同时相中SMCMP和血乳酸、SMCMP和骨骼肌组织ATP含量之间的相互关系,以期探讨休克时SMCMP的变化及其可能机
In vivo determination of Skeletal Muscle Cellular Membrane Potential (SMCMP) can directly reflect and monitor the changes of cell membrane and cell function in shock state, but the mechanism of SMCMP decline in shock is still controversial. In this study, “semi-floating” glass ultramicroelectrode technique was used to determine SMCMP in vivo, and the relationship between SMCMP and ATP content in blood lactic acid, SMCMP and skeletal muscle in different phases of hemorrhagic shock in rabbits , In order to explore the changes of SMCMP during shock and its possible mechanism