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Ludwig等早已报告延髓内有“血管运动中枢,”后来证明自写翮上方3毫米至上凹这一区域内,有调节动脉压的中枢,其内侧区为“减压区”,外侧为“加压区”。1979年Kuo等证明刺激大鼠的延髓网状巨胞核的腹侧区,可使心率减慢、血压降低;但并没有解决此区对心血管抑制作用的具体机制。作者用32只成年猫,在α-氯醛糖和乌拉坦麻醉的急性实验中,观察了电刺激或电解损毁网状巨胞核对基础动脉压和心率的影响,及其与脱羟肾上腺素、血管紧张肽、硝酸甘油
Ludwig et al. Have previously reported that there is a “vasomotor center” in the medulla oblongata, which later proved to be within 3 mm of the upper part of the upper part of the ephemeral fold. There is a central part for regulating arterial pressure, the medial region is “decompression zone” and the lateral is “ Area”. In 1979, Kuo et al demonstrated that the ventral region of the medulla oblongata giant cell in rats stimulated the heart rate and blood pressure to decrease, but did not solve the specific mechanism of cardiovascular inhibition in this area. In an acute experiment with α-chlorella and urethane anesthesia, 32 adult cats were used to investigate the effects of electrical or electrolytic destruction of reticulated macrophages on basal arterial pressure and heart rate, as well as their effects on the effects of phenylephrine, Angiotensin, nitroglycerin