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目的了解不同营养状况青少年胰岛素抵抗状况,为早期预防胰岛素抵抗提供理论依据。方法在北京市东城区选择初中三年级学生935名,进行身体测量、空腹血糖和胰岛素抵抗指标的测定。结果体重正常、超重和肥胖中学生胰岛素抵抗指标FINS(空腹胰岛素),HOMA-IR(稳态模型胰岛素抵抗指数),IAI(胰岛素敏感性指数)差异均有统计学意义(P值均<0.05),FPG差异无统计学意义(P>0.05)。随着BMI(体质指数)的升高,FINS,HOMR-IA,IAI绝对值逐渐升高。结论青少年肥胖与胰岛素抵抗存在一定相关性。超重和肥胖青少年已经出现胰岛素抵抗的现象,应重视并积极防治。
Objective To understand the status of insulin resistance in adolescents with different nutritional status and to provide a theoretical basis for early prevention of insulin resistance. Methods 935 junior high school students were selected in Dongcheng District of Beijing for body measurement, fasting blood glucose and insulin resistance. Results There were significant differences in FINS, HOMA-IR and IAI among overweight and obese middle school students with normal weight (P <0.05) FPG difference was not statistically significant (P> 0.05). With the increase of BMI (body mass index), the absolute value of FINS, HOMR-IA and IAI increased gradually. Conclusion There is a certain correlation between obesity and insulin resistance in adolescents. Overweight and obese adolescents have emerged insulin resistance phenomenon, should pay attention to and actively prevent and treat.