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采用动态心电图统计24小时全部窦性RR间期,以测定30例急性心肌梗塞(AMI)后17±4d的心率变异性(HRV)RR间期均值的标准差(SD)指标,并同时测定心室晚电位(VLP)、左室射血分数(LVEF)和用Holter记录室性心律失常,分析它们之间的关系。VLP阳性与阴性组的HRV无显著性差异(P>0.05);HRV与LVEF呈显著正相关(P<0.005);Holter记录到短阵室性心动过速、成对室性早搏(简称室早)和每小时室早数>100次的SD值显著低于未记录到室早和每小时室早数<10次者(P<0.001)。提示AMI后HRV降低与VLP阳性与否无关;低LVEF者HRV亦降低;HRV降低者其室性心律失常发生率显著增加。联合应用上述方法和指标,可望提高对AMI后高危患者预测的准确率。
The 24-hour total sinus RR interval was measured by Holter monitoring to measure the standard deviation (SD) of RR interval mean of heart rate variability (HRV) at 17 ± 4 days after 30 patients with acute myocardial infarction (AMI) (VLP), left ventricular ejection fraction (LVEF) and ventricular arrhythmias recorded with Holter, and analyzed the relationship between them. There was no significant difference in HRV between VLP positive group and negative group (P> 0.05). There was a significant positive correlation between HRV and LVEF (P <0.005). Holter recorded paroxysmal ventricular tachycardia, (SD) and morning premature> 100 times per hour were significantly lower than those who did not record premature ventricular contractions <10 times per hour (P <0.001). It is suggested that the decrease of HRV after AMI has nothing to do with the positive of VLP; the HRV of low LVEF is also decreased; the incidence of ventricular arrhythmia is significantly increased when HRV is decreased. The combined use of the above methods and indicators is expected to improve the accuracy of the prediction of high-risk patients after AMI.