目的了解肝硬化合并感染的状况和对转归的影响。方法以３０７例肝硬化患者为研究对象，结合临床、实验室检查及转归进行分析。结果７３例合并各种院内外感染，感染发生率为２３．７８％。医院感染率为１０．４２％，老年组医院感染发生率（１４．５１％）明显高于非老年组（７．１０％）；本组肝硬化患者的总死亡率为１６．２９％，合并感染者的死亡率（３８．３６％）明显高于无合并感染者（９．４０％）；多系统感染者死亡率（５３．８４％）明显高于单一系统感染者；合并感染的老年患者的死亡率（２８．５７％）虽然低于非老年组（４４．４４％），但老年患者易发生感染性休克，且不易纠正而直接导致死亡。结论肝硬化患者易并发各种感染，是造成病情恶化导致死亡的重要原因 Objective To understand the status of cirrhosis complicated with infection and its impact on the outcome. Methods 307 cases of cirrhosis patients for the study, combined with clinical, laboratory tests and outcome analysis. Results 73 cases combined with various hospital infections, the incidence of infection was 23.78%. Hospital infection rate was 10.42%, the incidence of nosocomial infection in the elderly group was significantly higher than that in the non-elderly group (7.10%); the total mortality rate in patients with cirrhosis was 16.29% The mortality of infected persons (38.36%) was significantly higher than that of non-infected persons (9.40%). The mortality rate of multi-system infection (53.84%) was significantly higher than that of single-system infected patients (28.57%) was lower than the non-elderly group (44.44%). However, septic shock was more likely to occur in elderly patients and was not easily corrected to directly cause death. Conclusions Patients with cirrhosis complicated by various infections are the important causes of death caused by the worsening of the disease