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由于甲型流感病毒血凝素具有高度变异性，故其抗血凝素单抗不适于甲型流感病毒感染的病原学诊断。我们应用甲型流感病毒内部抗原D91-11免疫BALB/c小鼠，取其脾细胞与小鼠骨髓瘤细胞NS－1融合，获得3林稳定分泌抗甲型流感病毒内部抗原的单克隆抗体细胞株1A9、1B1和1D4，阳性率为
Due to the high degree of variability of influenza A hemagglutinin, its anti-hemagglutinin monoclonal antibody is not suitable for the etiological diagnosis of influenza A virus infection. BALB / c mice were immunized with influenza A virus internal antigen D91-11 and their spleen cells were fused with mouse myeloma NS-1 cells to obtain 3 monoclonal antibody cells stably secreting anti-influenza A virus internal antigens Strain 1A9, 1B1 and 1D4, the positive rate of