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对１９９３～１９９６年住院治疗的２５例骨转移癌患者采用单用骨膦治疗的方法，观察其对骨转移癌患者的止痛效果、骨病灶变化和不良反应。结果∶疼痛完全缓解５例（２０％），部分缓解１１例（４４％），无效９例（３６％），总有效率为６４％；骨病灶控制率为１２％（３／２５）；不良反应仅有轻微恶心。提示∶骨膦是治疗骨转移癌较理想的药物。
Twenty-five patients with metastatic bone cancer admitted to hospital from 1993 to 1996 were treated with osteophosphamide alone to observe their analgesic effects, bone lesions and adverse reactions in patients with metastatic bone. Results: Complete pain relief was achieved in 5 cases (20%), partial remission in 11 cases (44%), ineffectiveness in 9 cases (36%), total effective rate was 64%, bone lesions control rate was 12% (3/25) The reaction is only slight nausea. Tip: Bonephosphate is the ideal drug for the treatment of bone metastases.