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目的观察博宁对前列腺癌骨转移的止痛效果。方法37例患者分别接受博宁(简称单用组)或博宁+联合化疗(简称联合组)治疗。结果骨痛总缓解率为80%,单用组及联合化疗有效率分别为77.1%和82.8%,两组比较差异无显著性。除少数患者出现胃肠道反应外,无明显其他毒副反应。结论博宁是一种安全、有效的双膦酸制剂,可用于前列腺癌骨转移患者的治疗。
Objective To observe the pain relief effect of Boning on bone metastasis of prostate cancer. Methods Thirty-seven patients were treated with Bonin (single used group) or Bonin + combined with chemotherapy (referred to as combined group) respectively. Results The total pain relief rate was 80%. The effective rates of single and combined chemotherapy were 77.1% and 82.8% respectively. There was no significant difference between the two groups. In addition to a small number of patients with gastrointestinal reactions, no other obvious side effects. Conclusion Bonin is a safe and effective bisphosphonate preparation for the treatment of patients with prostate cancer with bone metastases.