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目的 分析严重急性呼吸道综合征 (SARS)抗病毒治疗的时机 ,为制定SARS抗病毒治疗方案提供参考。方法 采用临床流行病学回顾研究 ,使用SPSS软件分析我院SARS患者的住院病历特点及转归 ,分析不同时间开始抗病毒治疗对T细胞亚群以及预后的影响 ,以初步探讨SARS抗病毒治疗的时机。结果 本文研究发现 ,随着抗病毒治疗开始时间的延迟 ,T细胞亚群的下降程度明显增加 ,病死率逐渐上升 ;发病 3d内开始抗病毒治疗治愈率可达 10 0 % ,而在发病第 4～ 7天时才开始抗病毒治疗的病死率已超过文献报道 ( 6 5 % )水平。结论 发病 3d内开始抗病毒治疗效果比较好。
Objective To analyze the timing of antiviral therapy in patients with severe acute respiratory syndrome (SARS) and provide references for the development of antiviral treatment programs for SARS. Methods The clinical epidemiological retrospective study of the use of SPSS software analysis of our hospital SARS patients characteristics and prognosis of hospitalized patients with different time to analyze the impact of antiviral therapy on T cell subsets and prognosis of the SARS antiviral treatment opportunity. Results The study found that, with the onset of anti-viral treatment delay, T cell subpopulation decreased significantly increased, the mortality rate increased gradually; the onset of 3d antiviral therapy, the cure rate of up to 10%, while the incidence of 4 The mortality rate of antiviral treatment starting at ~ 7 days has exceeded the reported level (65%). Conclusion The onset of antiviral therapy within 3 days is better.