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目的:研究草苁蓉提取物(BRE)的抗脂质过氧化活性。方法:用分光光度法测定肝匀浆和肝线粒体的总抗氧化能力、抗活性氧能力以及H2O2和Fe2++H2O2诱导的肝匀浆和肝线粒体丙二醛(MDA)含量。结果:BRE可明显提高肝匀浆和肝线粒体总抗氧化能力和活性氧清除能力,明显抑制肝匀浆和肝线粒体脂质过氧化作用。结论:BRE具有抗脂质过氧化活性。
Objective: To study the anti-lipid peroxidation activity of Cistanche desertica extract (BRE). Methods: The total antioxidant capacity and anti-reactive oxygen species in liver homogenate and liver mitochondria were measured by spectrophotometry. The content of malondialdehyde (MDA) in liver homogenate and liver mitochondria induced by H2O2 and Fe2 + + H2O2 were measured. Results: BRE significantly increased the total antioxidant capacity of liver homogenate and hepatic mitochondria and scavenging capacity of reactive oxygen species, and significantly inhibited the lipid peroxidation of liver homogenate and liver mitochondria. Conclusion: BRE has anti-lipid peroxidation activity.