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目的探讨齐拉西酮联合心理干预在青少年精神分裂症中的临床疗效。方法选取2014年1月~2016年12月医院收治青少年精神分裂症患者90例,随机分为对照组(n=45)和观察组(n=45)。对照组采用齐拉西酮治疗,观察组在对照组的基础上联合心理干预治疗,采用阳性和阴性症状量表(PANSS)对两组治疗效果进行评估。结果观察组治疗后有效率为94.1%,对照组为67.6%,两组差异有统计学意义(P<0.05);治疗后,观察组治疗后阳性量表、阴性量表、一般病理及量表总分均低于对照组(P<0.05)。结论青少年精神分裂症患者在齐拉西酮基础上联合心理干预治疗效果理想,值得推广应用。
Objective To investigate the clinical efficacy of ziprasidone combined with psychological intervention in adolescent schizophrenia. Methods Ninety adolescents with schizophrenia admitted to our hospital from January 2014 to December 2016 were randomly divided into control group (n = 45) and observation group (n = 45). The control group was treated with ziprasidone. The observation group was treated with psychological intervention on the basis of the control group, and the positive and negative symptom scales (PANSS) were used to evaluate the therapeutic effect of both groups. Results After treatment, the effective rate was 94.1% in the observation group and 67.6% in the control group, with significant difference between the two groups (P <0.05). After treatment, the positive and negative scales, general pathology and scale The total score was lower than the control group (P <0.05). Conclusion Adolescent schizophrenia patients combined with ziprasidone based on psychological intervention is effective and worthy of promotion.