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目的 探讨急性渗出性前葡萄膜炎与HLA-B27的相关性。方法 对53例前房内出现成型性渗出的急性前葡萄膜炎（AAUPE）患者及61例前房内无成型性渗出的急性前葡萄膜炎（AAU）患者进行HLA-B27的检测,并结合临床表现加以分析。结果 成型性渗出的AAUPE患者的HLA-B27阳性率为100％,而无成型性渗出的AAU患者的HLA-B27阳性率仅为50.8％。二者有显著差异性（P<0.01）。两组HLA-B27阳性的病人强直性脊柱炎发生率分别为50.0％和42.9％。结论 结果进一步证实了HLA-B27与成型性渗出密切相关的论点。提示检测AAU患者HLA-B27的阳性率,发现成型性渗出裂隙灯检查似与血清法检测同样准确。
Objective To investigate the correlation between acute exudative anterior uveitis and HLA-B27. Methods HLA-B27 was detected in 53 cases of AAU with anomalous exudation in the anterior chamber and 61 cases of anterior uveal exudative AAU in the anterior chamber. Combined with clinical manifestations to be analyzed. Results The positive rate of HLA-B27 in AAUPE patients with invasive exudation was 100%, while the positive rate of HLA-B27 in AAU patients without invasive exudation was only 50.8%. There was significant difference between the two (P <0.01). The incidence of ankylosing spondylitis in two HLA-B27-positive patients was 50.0% and 42.9%, respectively. Conclusions The results further confirm the conclusion that HLA-B27 is closely associated with invasive exudation. Prompt detection of HLA-B27 in patients with AAU positive rate and found that exudative slit lamp examination and serum test as accurate.