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目的:观察小剂量巯甲丙脯酸治疗神经心源性晕厥的疗效及安全性。方法:21 例神经心源性晕厥患者均口服巯甲丙脯酸6.25m g,每日3 次,用药时严密观察心率、血压、心电图及晕厥发作情况。结果:21例患者服药后均未再出现晕厥发作(随诊期8~20个月不等),倾斜试验转阴。服药期间2 例患者出现轻咳,后自行缓解。结论:小剂量巯甲丙脯酸治疗神经心源性晕厥是一种行之有效而又安全可靠的方法,值得推广应用。
Objective: To observe the efficacy and safety of low-dose captopril in the treatment of neurocardic syncope. Methods: Twenty-one patients with neuropsychiatric syncope were orally administered with captopril 6.25 mg once daily for 3 times. Heart rate, blood pressure, electrocardiogram and syncope were monitored closely. Results: All the 21 patients did not have syncope again after the treatment (the follow-up period was 8-20 months). The tilt test turned negative. 2 patients during medication with light cough, self-remission. Conclusion: The low dose of captopril in the treatment of neurocardic syncope is an effective and safe method, which is worth popularizing and applying.