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目的：探讨高原地区胸部火器伤邻近肝组织损伤特点。方法：实验犬分对照组和预防组各１５只病理学观察。结果：对照组均见肝脏不同程度的出血，血管内皮细胞间隙增宽，微饮泡增多。肝细胞灶性坏死，线粒体肿胀空化，核固缩，染色质减少，局部肝细胞膜破裂，内容物溢出。预防组仅见２ 例点状出血，血管内皮轻度肿胀，线粒体肿胀而少见空化。结论：提示在高速投射物伤的早期救治阶段，应注意肝功的监测和维护。
Objective: To investigate the characteristics of adjacent liver injury in chest firearm injuries in plateau. Methods: The experimental dogs divided into control group and prevention group of 15 pathological observation. Results: The control group showed varying degrees of bleeding in the liver, broadening of the gap between the vascular endothelial cells and micro-feeding of cans. Focal liver cell necrosis, mitochondria swelling cavitation, nuclear pyknosis, chromatin reduction, local liver cell membrane rupture, the contents of overflow. Preventive group only seen 2 cases of punctate bleeding, mild swelling of vascular endothelium, mitochondria swelling and cavitation rarely. Conclusion: It is suggested that monitoring and maintenance of liver function should be paid attention in the early stage of treatment of high-speed projectile injuries.