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目的:半胱氨酸蛋白酶抑制剂C是一个评价肾功能的新指标,被认为是心血管疾病的预后标记物。本研究探讨半胱氨酸蛋白酶抑制剂C与其他肾功能指标及NT-proBNP相比,在急性心力衰竭患者中的预后预测价值。方法和结果:纳入一项前瞻性、多中心的急性心力衰竭研究中测定了半胱氨酸蛋白酶抑制剂C水平的480例患者。12个月全因死亡率为25.4%。
PURPOSE: Cystatin C is a new indicator of renal function and is considered as a prognostic marker of cardiovascular disease. This study investigated the prognostic value of cystatin C in patients with acute heart failure compared with other renal function parameters and NT-proBNP. Methods and Results: Forty-eight patients with a Cysteine Protease Inhibitor C level were included in a prospective, multicenter study of acute heart failure. The 12-month all-cause mortality rate was 25.4%.