INTRODUCTIONrnYAP (yes?associated protein) is a transcriptional cofactor that is highly related to TAZ (transcriptional co?activator with PDZ binding motif). Bo
INTRODUCTIONrnWnt signaling plays key roles in many aspects of development and adult tissue homeostasis.1–2 WNTs are secreted palmitoleated glycoprotein ligand
INTRODUCTIONrnBone remodeling is a lifelong process in vertebrates that relies on the balance between bone formation by osteoblasts and bone resorption by osteo
INTRODUCTIONrnTotal joint arthroplasty is a common orthopedic surgical procedure with not only significant benefits but also challenging complications, especial
INTRODUCTIONrnOsteosarcoma is the most common type of primary bone sarcoma that mostly occurs in teenagers and young adults.1 Osteosarcoma usually grows in the