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1979～1990年作者共放疗117例视网膜母细胞瘤(RB),其中97例双眼RB,20例单眼RB。男:女=56:61,中位年龄7个月(<1～60月),均行放疗,野不包松果体区。19例因复发或转移用了化疗,随访4～153月(中位68月),以Kaplan-Meiter方法计算第三眼RB(TRB)发病率。结果共6例TRB,都见于双眼RB,发病率为6％(6/97例);有RB家族史者TRB发病率为10％;TRB患儿确诊RB时年龄<1～7月(中
A total of 117 patients with retinoblastoma (RB) were treated with radiotherapy from 1979 to 1990, of which 97 eyes were binocular RB and 20 eyes were monocular RB. Male: Female = 56:61, median age 7 months (<1 ~ 60 months), were treated with radiotherapy, wild not wrapped pineal area. Twenty-nine patients received chemotherapy for relapse or metastasis and were followed up for 4 to 153 months (median 68 months). The incidence of RB (TRB) in the third eye was calculated using the Kaplan-Meiter method. Results A total of 6 cases of TRB were found in binocular RB, the incidence rate was 6% (6/97 cases). The incidence of TRB was found in 10% of cases with RB family history. The mean age at diagnosis of TRB was <1 ~ 7 months