本文讨论:(1)抑制素是睾丸支柱细胞分泌的蛋白质,它选择性地抑制垂体分泌FSH。目前尚无提纯的制剂。(2)切除睾丸即无抑制素时,血浆睾丸酮水平的降低及伴随的血浆雌二醇水平的相对升高也可导致上述血清FSH及LH分泌的分离,此时血清PRL水平也升高。著者认为可能这两种调节因素的作用是相辅相成的。 This article discusses: (1) Inhibin is a protein secreted by testicular stromal cells that selectively inhibits the secretion of FSH by the pituitary gland. There are currently no purified preparations. (2) When testis is absent of inhibin, the decrease of plasma testosterone and the relative increase of plasma estradiol level can also lead to the separation of the serum FSH and LH secretion, and the serum PRL level also rises. The authors believe that it is possible that the roles of these two mediators are mutually reinforcing.