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本文报告２２１例临床诊断为巨脾型晚期血吸虫病（晚血）患者肝组织病理检查结果，其中单纯血吸虫性肝纤维化１３１例（５９．３％），血吸虫性肝纤维化合并肝炎（伴肝细胞变性、坏死）４２例（１９．０％），肝炎肝硬化２７例（１２．２％），慢性肝炎１３例（５．９％），其它疾病８例（３．６％），表明肝炎及肝炎肝硬化是误诊为晚血的主要疾病。随访２～７年１７７例，死亡２９例，病死率１６．４％，肝炎肝硬化及血吸虫肝纤维化伴肝细胞病变者病死率均显著高于单纯血吸虫肝纤维化患者（Ｐ＜０．０５），多数患者死于肝衰竭及原发性肝癌。死于上述肝病者均存在ＨＢＶ和／或ＨＣＶ感染，提示ＨＢＶ及ＨＣＶ感染是晚血发生肝衰竭及肝癌的关键因素，与患者死亡密切相关。
This paper reports 221 cases of clinical diagnosis of splenic type of advanced schistosomiasis (late blood) patients with liver histopathological examination results, including 131 cases of schistosomal liver fibrosis (59.3%), schistosomiasis of liver fibrosis with hepatitis (19.0%), hepatic cirrhosis in 27 cases (12.2%), chronic hepatitis in 13 cases (5.9%) and other diseases in 8 cases (3.6%), indicating that hepatitis And hepatitis cirrhosis is misdiagnosed as the main disease of late blood. 177 cases were followed up for 2 to 7 years, 29 died, the case fatality rate was 16.4%. The mortality rate of liver cirrhosis and schistosomiasis hepatic fibrosis with hepatocellular disease were significantly higher than those of schistosomiasis patients with hepatic fibrosis (P <0.05 ), Most of the patients died of liver failure and primary liver cancer. HBV and / or HCV infection is found in all those who died of the above-mentioned liver diseases, suggesting that HBV and HCV infection are the key factors of liver failure and liver cancer in late-onset blood and are closely related to the death of the patients.