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为了解小儿与成人肾病综合征(NS)病理及临床疗效差异。对同期住院的小儿与成人把各350例的临床分型、病理类型及疗效进行比较。结果小儿组中,单纯性肾病占77.1%(270例),肾炎性肾病占22.9%(80例);成人组中,NSI占44.9%(157例)、NSII占55.1%(193例)。病理类型:MCD、MsPGN、IgAN、EnP小儿多于成人,MN、FsGS、MPGN、CrGN成人较小儿多见,PSGN、SGN仅见于成人。小儿组完全缓解82.6%,成人组完全缓解67.1%。结论:小儿组以单纯性肾病最多见,成人组以NSⅡ多见,小儿组病理改变数成人组轻,疗效小儿组明显优于成人组。
To understand the pediatric and adult nephrotic syndrome (NS) pathological and clinical differences. On the same period hospitalized children and adults to the clinical classification of 350 cases, pathological types and efficacy were compared. Results In the pediatric group, 77.1% (270 cases) of pure nephropathy and 22.9% (80 cases) of nephritis were found. In the adult group, NSI accounted for 44.9% (157 cases) and NSII accounted for 55%. 1% (193 cases). Pathological types: MCD, MsPGN, IgAN, EnP Children more than adults, MN, FsGS, MPGN, CrGN adults more common in children, PSGN, SGN only seen in adults. Complete remission was 82.6% in pediatric group and 67.1% in adult group. Conclusion: The most common type of nephropathy is pediatric group. The NS Ⅱ is more common in adults and the pathological changes in pediatric group are lighter than those in adult group. The curative effect in pediatric group is obviously better than that in adult group.