论文部分内容阅读
一、原发性血小板减少性紫癜(ITP) ITP是自身免疫性疾病。近年来抗血小板抗体的检查法虽不断改良更新,但尚未有确定的检查法。然而抗血小板抗体的对应抗原——血小板膜糖蛋白(GP)Ⅱb/Ⅲa和GPIb/Ⅸ等作为血小板自身抗原已被检出。虽然目前的方法检出率尚低,但今后随着检查方法的进步,检出率的提高,将会有助于自身抗原种类与ITP的病型,病理和治疗效果之间关系的研究。对慢性ITP的治疗,首选药仍然是糖皮质激素(P)。若该药无效或因副作则不能耐受时,则应早期摘脾。摘脾是本病最可靠的疗
First, idiopathic thrombocytopenic purpura (ITP) ITP is an autoimmune disease. In recent years, anti-platelet antibody test, although the continuous improvement of the update, but there is no definitive test. However, anti-platelet antibodies corresponding antigen - platelet membrane glycoprotein (GP) Ⅱ b / Ⅲ a and GPIb / Ⅸ as platelet autoantigen has been detected. Although the detection rate of the current method is still low, the improvement of the detection rate in the future will help to study the relationship between the type of autoantigen and the type, pathology and therapeutic effect of ITP. For the treatment of chronic ITP, the preferred drug is still glucocorticoid (P). If the drug is invalid or can not be tolerated because of side effects, it should be early spleen. Pick the spleen is the most reliable treatment of this disease