测定经培养的羊水细胞中酶活性进行溶酶体贮积症的产前诊断,国外已普遍应用,国内也已开始。此法的缺点在于羊膜腔穿刺须在16～20孕周进行。羊水细胞再经培养2～3周。待做出判断妊娠业已19～23周,增加了孕妇的痛苦。因此国外近年已有在孕早期取绒毛组 Determination of the activity of cultured amniotic fluid cells to carry out prenatal diagnosis of lysosomal storage disease, has been widely used abroad, the country has also begun. The disadvantage of this method is that amniocentesis should be carried out in 16 to 20 gestational weeks. Amniotic fluid cells and then cultured for 2 to 3 weeks. To be made to judge the pregnancy has been 19 to 23 weeks, an increase of pregnant women’s pain. Therefore, foreign countries in recent years have been taken in the early flu group