吸烟和氡对于诱发肺癌具有联合作用,在混合人群(吸烟者与非吸烟者)中不可能真正检测出氡在致肺癌中的主要效应。本文就在混合人群和非吸烟人群中的病例一对照研究的设计方案进行了评价。混合人群中的病例一对照研究选用具有公共卫生学意义的归因危险度(AR)作为待检效应的可检测水平,且该混合人群的吸 Smoking and sputum have a joint effect on the induction of lung cancer. It is impossible to truly detect the main effects of sputum in lung cancer in mixed populations (smokers and non-smokers). This article evaluated the design of a case-control study in mixed and non-smoking populations. A case-control study in a mixed population used a public health risk of attribution (AR) as a detectable level of the effect to be examined, and the mixed population was