对11例4～14岁的瓣膜病变患儿进行儿童瓣膜置换术，其中4例合并有其他心脏畸形予以同期修复，无住院死亡。晚期死亡1例，存活者心功能Ⅰ～Ⅱ级。认为：小儿应首选机械瓣；抗凝治疗是术后的主要问题；对左侧位（主动脉瓣、二尖瓣）瓣膜术后应用小剂量抗凝剂在凝血酶原时间标准化比值监测下是安全的；儿童应尽可能选用符合成人需要型号的瓣膜。 Eleven children aged 4 to 14 years with valvular disease underwent valve replacement surgery, of which 4 cases were complicated with other cardiac malformations and were not hospitalized for death. 1 case of late death, heart function of survivors Ⅰ ~ Ⅱ level. It is considered that mechanical flap should be the first choice in children and anticoagulant therapy is the main problem after operation. The application of low-dose anticoagulant to the valve on the left side (aortic valve and mitral valve) after prothrombin time standardization is Safe; children should use as much as possible to meet the adult needs of the valve model.