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目的:观察辛伐他汀(舒降之)治疗高脂血症的临床疗效。方法:对76例高脂血症患者给予口服辛伐他汀20m g/d,治疗8周。治疗前、后分别测定胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)等。结果:治疗前后血脂水平比较差异有统计学意义(P均<0.01),治疗后血脂降低效果明显。服药期间部分患者出现消化道反应及一过性ALT、A ST增高等不良反应。结论:辛伐他汀调脂疗效好,不良反应少。
Objective: To observe the clinical efficacy of simvastatin (SHR) in the treatment of hyperlipidemia. Methods: 76 patients with hyperlipidemia were given simvastatin 20 m g / d for 8 weeks. Cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) were measured before and after treatment. Results: Before and after treatment, there was significant difference in the level of blood lipids (P <0.01), and the effect of lowering blood lipids was obvious after treatment. Some patients during the administration of gastrointestinal reactions and transient ALT, STS increased adverse reactions. Conclusion: Simvastatin is effective in regulating lipids and has few adverse reactions.