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目的评价核素显像在乳腺肿块诊断中的价值。方法应用９９ｍ锝－甲氧基异丁基异腈（９９ｍＴｃ－ＭＩＢＩ）核素显像技术检查女性乳房肿块３８例和乳腺癌局部切除术后２例。结果术后病理确诊为乳腺癌的２４例中，术前２１例９９ｍＴｃ－ＭＩＢＩ显像为阳性：而１４例良性乳腺肿块中，１０例显像为阴性。该法检测乳腺癌的灵敏度为８７．５％，特异性为７１．４％，准确性为８１．６％。９例乳腺癌腋下淋巴结转移者中术前显像阳性３例，８例乳腺癌扩大根治术者中术前显像阳性２例，均与病理检查结果相符。结论９９ｍＴｃ－ＭＩＢＩ显像对于鉴别乳腺良恶性肿块有一定价值。
Objective To evaluate the value of radionuclide imaging in the diagnosis of breast masses. Methods Thirty-eight cases of breast tumor and two cases of breast cancer after partial resection were examined with 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) imaging. Results Of the 24 cases diagnosed as breast cancer pathologically, 21 cases of 99mTc-MIBI imaging were positive before surgery. Of the 14 cases with benign breast mass, 10 cases were imaging negative. Breast cancer detection sensitivity of the method was 87.5%, specificity was 71.4%, accuracy was 81.6%. Preoperative imaging was positive in 9 cases of breast cancer with axillary lymph node metastasis, and 2 cases were positive in 8 cases of breast cancer with radical mastectomy. The results were consistent with the pathological findings. Conclusion 99mTc-MIBI imaging has certain value in differentiating benign and malignant breast tumors.