Creutzfelt—Jakob二氏病(简称CJD),又名亚急性海绵样脑病或皮质—纹状体—脊髓变性,是一种慢病毒引是的罕见的中枢神经变性疾病。CJD散发于全世界,发病率在西方国家约为每10万人口中一例,死亡率为每年每两百万人口一例,目前世界上已报道1600余例。国内冯氏报告1例,丘氏报告2例,本文报告兰州地区证实的第一例CJD。患者王某,男性,61岁,四川籍,1987,10, Creutzfelt-Jakob’s disease (CJD), also known as subacute spongiform encephalopathy or cortical-striatal-spinal cord degeneration, is a rare degenerative CNS disease caused by lentivirus. The CJD is distributed throughout the world and its incidence is about one in every 100 000 in western countries. The mortality rate is one case per two million people each year, and more than 1,600 cases have been reported in the world at present. 1 case of domestic Feng’s report, 2 cases of Chiu’s report, this paper reports the first case of CJD confirmed in Lanzhou. Patient Wang, male, 61 years old, Sichuan membership, 1987,10,