论文部分内容阅读
目的探讨甲氨蝶呤联合米非司酮治疗输卵管妊娠的疗效。方法对确诊为输卵管妊娠86例患者分为2组。联合用药组45例,甲按蝶呤50mg加注射用水20ml/次、静脉推注,口服米非司酮75mg,2次/d共5d。米非司酮组41例,单纯口服米非司酮75mg,2次/d共5d。2组病例均在用药后5d复查血β-HCG及B超,血β-HCG下降>15%。B超提示盆腔情况改善或无加重,重复下1个疗程。结果联合用药组疗效95.55%,米非司酮组疗效75.60%,2组疗效有可比性(P<0.05)。结论联合用药保守治疗输卵管妊娠疗效确切,无明显不良反应。
Objective To investigate the efficacy of methotrexate combined with mifepristone in the treatment of tubal pregnancy. Methods 86 cases diagnosed as tubal pregnancy were divided into two groups. Combination of 45 cases, methotrexate 50mg plus water 20ml injection, intravenous injection, oral mifepristone 75mg, 2 times / d for 5 days. Mifepristone group 41 cases, simple oral mifepristone 75mg, 2 times / d 5d. Both groups were examined for blood β-HCG and B-ultrasound 5 days after treatment, and blood β-HCG decreased by> 15%. B-Tip pelvic improvement or no improvement, repeat the next course of treatment. Results The efficacy of combined treatment group was 95.55%, mifepristone group 75.60%, the two groups were comparable (P <0.05). Conclusions The conservative treatment of tubal pregnancy with combined treatment is effective and has no obvious adverse reactions.