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尽管有不同的病因学说,鼻息肉仍然是一种了解甚少的临床常见病。从筛窦和下呼吸道组织中发现的组织学特征很像由单一病因引起的病变。现有两种关于病因的学说,过敏说和感染说。过敏学说是根据组织学表现,嗜酸性白细胞显著增加,而不是根据临床病史。Bickmore(1981)指出:枯草热很少伴发鼻息肉,但有枯草热的鼻息肉患者,息肉可能出现较早。Moloney等(1977)认为哮喘常伴鼻息肉发生。过敏性主要通过附着于肥大细胞表面的、有抗原特异性的IgE 作用。当抗原存在时,这些肥大细胞脱颗粒。还有很多能引起肥大细胞脱颗粒的其他原因,这
Although there are different etiologies, nasal polyps are still a poorly understood clinical common problem. Histological features found in the ethmoid and lower respiratory tract tissues are much like those caused by a single cause. There are two theories about etiology, allergens and infections. The theory of allergy is based on histological manifestations, with a significant increase in eosinophils rather than on clinical history. Bickmore (1981) pointed out: hay fever rarely associated with nasal polyps, but hay fever patients with polyps, polyps may appear earlier. Moloney et al (1977) that asthma often accompanied by nasal polyps. Allergicity mainly through the attached to the surface of mast cells, antigen-specific IgE role. When antigens are present, these mast cells degranulate. There are many other reasons that can cause degranulation of mast cells