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呼吸道病毒感染是一种常见疾病,目前对其早期诊断和治疗的方法较少。为寻找早期诊断和治疗病毒感染的方法,1972年在复查呼吸道疾病患者的支气管细胞涂片时,发现一例临床诊断为“病毒性肺炎”患者的支气管细胞涂片中有大量特殊病变的纤毛上皮细胞。查阅国外文献,见Papaniclaou等作者曾先后报导:呼吸道病毒感染可引起纤毛柱状上皮细胞发生特殊病理改变,这种改变称为“纤毛细胞坏变”即Ciliocytophtheria,简称“CCP”,并以此作为诊断病毒感染的指标,但未见到同时作病毒分离和系统研究的报导。
Respiratory virus infection is a common disease, the current method of early diagnosis and treatment of less. In an effort to find an early diagnosis and treatment of viral infections, a review of bronchial cell smears of patients with respiratory diseases in 1972 found that a large number of particularly diseased ciliated epithelial cells were found in bronchial smears from patients with clinically diagnosed “viral pneumonia” . Access to foreign literature, see Papaniclaou and other authors have successively reported: respiratory virus infection can cause ciliated columnar epithelial cells with special pathological changes, this change is called “ciliocytosis” or Ciliocytophtheria, referred to as “CCP”, and as a diagnosis Virus infection indicators, but did not see at the same time for virus isolation and systematic research reports.