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目的探讨采用中心静脉导管行胸腔闭式引流治疗AECOPD合并自发性气胸的临床疗效。方法分别采用传统胸腔闭式引流和中心静脉导管行胸腔闭式引流两种方法，对我院2010年1月~2014年12月收治的78例AECOPD合并自发性气胸患者进行治疗,讨论两种治疗方式的优缺点。结果传统胸腔闭式引流治疗AECOPD合并自发性气胸患者全部治愈（平均留置导管天数（6.21±0.38）d，住院天数（21.71±0.8）d），中心静脉导管引流治疗AECOPD合并自发性气胸患者全部治愈（平均留置导管天数（3.76±0.73）d，住院天数（12.59±1.3）d），二者比较具有统计学意义。结论对AECOPD合并自发性气胸患者采用中心静脉导管行胸腔闭式引流术治疗,是一种简便、安全、有效的方法，值得临床推广。“,”Objective To evaluate the application value of the central venous catheter closed drainage in the treatment of AECOPD with spontaneous pneumothorax. Methods 78 AECOPD with spontaneous pneumothorax patients from January in 2010 to December in 2014 were divided into two groups:traditional closed troracic drainage and central venous catheter closed drainage to compare the clinical ef ects. Results Compared with traditional closed troracic drainage, central venous catheter closed drainage can shorten the average number of days intubation (3.76±0.73d vs 6.21±0.38d) and duration of treatment (12.59±1.3d vs 21.71±0.8d). Conclusion Central venous catheter closed drainage is a kind of easy, ef ective and safe way in the treatment of AECOPD with spontaneous pneumothorax.