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作者报导用利多卡因静注治疗8例安定(DZP)和苯妥因钠(PHT)静注无效或/和伴有慢性阻塞性肺部疾患(COLD)的癫痫状态患者,结果均迅速使发作停止。60年代中期以来,PHT 和DZP 静注使95%原发性大发作和65%部分发作引起的癫痫状态获得迅速控制。但仍有部份病例要静注苯巴比妥(PB)或全麻才能控制。静注DZP 或PB,还是全麻都难免引起或加重肺部感染,影响肺通气,换气功能,特别是老年患者。利多卡因则无呼吸抑制作用。动物实验及临床报导已证实了其抗痈作用。本组8例癫痫状态病人:其中原发性全身性发作2例及部分性继发性发作6例。5例静注PHT(总量18mg/kg)和DZP(总量20mg)无效,首剂静注
The authors report that intravenous injection of lidocaine in eight patients with epilepsy with intravenous infusion of diazepam (DZP) and phenytoin sodium (PHT) or / and chronic obstructive pulmonary disease (COLD) resulted in rapid onset stop. Since the mid-1960s, intravenous PHT and DZP resulted in rapid control of epileptic states caused by 95% of primary episodes and 65% of seizures. However, there are still some cases to be intravenous phenobarbital (PB) or general anesthesia in order to control. Intravenous DZP or PB, or general anesthesia are inevitable to cause or aggravate lung infection, affecting lung ventilation, ventilation, especially in elderly patients. Lidocaine has no respiratory depression. Animal experiments and clinical reports have confirmed its anti-tonic effect. The group of 8 patients with epilepsy: one of the two cases of primary systemic seizures and partial seizures in 6 cases. 5 cases of intravenous PHT (total 18mg / kg) and DZP (total 20mg) invalid, the first intravenous injection