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目的:探讨妊高征孕妇肾功能指标的变化,对妊高征肾功能受损指标与正常妊娠孕妇肾功能指标作对比分析。方法:对58例妊高征孕妇及60例正常妊娠孕妇分别进行尿素(UREA)、肌酐(C r)、尿酸(UA)、钙(C a)、镁(M g)测定。结果:妊高征孕妇血清钙(C a)、镁(M g)浓度均低于对照组(P<0.01);而血清尿素(UREA)、肌酐(C r)、尿酸(UA)水平与对照组比显著增高(P<0.01),且血清钙、镁浓度的降低和尿酸水平的增高与妊高征病情的严重程度成正相关。结论:及早检测妊高征孕妇肾功能的变化对疾病的诊断及预防并发征发生有一定的临床意义。
Objective: To investigate the changes of renal function indexes of pregnant women with PIH, and to compare the renal function indexes of pregnant women with PIH with those of normal pregnant women. Methods: UREA, C r, UA, Ca and Mg in 58 PIH pregnant women and 60 normal pregnant women were measured respectively. Results: The levels of serum calcium (Ca) and magnesium (Mg) in pregnant women with PIH were significantly lower than those in the control group (P <0.01). The levels of UREA, Cr, (P <0.01), and the decrease of serum calcium and magnesium concentration and the increase of uric acid level were positively correlated with the severity of PIH. Conclusion: Early detection of changes in renal function in pregnant women with PIH has certain clinical significance for the diagnosis and prevention of complications.