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双氯灭痛(Diclofenac sodium)为第三代非甾体抗炎药。因其疗效高且副作用小,临库用药更趋广泛,销售额仍在持续上升。双氯灭痛合成工艺路线众多。但以邻氯苯乙酸路线一步合成成品,适合于工业
Diclofenac sodium is the third-generation non-steroidal anti-inflammatory drug. Because of its high efficacy and small side effects, clinical drugs are more widely used, sales are still rising. Diclofenac synthesis process route many. However, the process of o-chlorophenylacetic acid one-step synthesis of finished products, suitable for industrial