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目的:分析探讨手足口病患儿心肌酶的变化情况。方法:对2011年9月～2011年11月期间在我院确诊并住院治疗的80例手足口病患儿及30例在我院进行常规体检儿童的临床资料进行回顾性研究。我们将这80例手足口病患儿作为观察组,将30例在我院进行常规体检的儿童作为对照组。我们在观察组患儿住院的当日或次日对其进行的心肌酶检验,在对对照组儿童进行常规体检时对其进行心肌酶检验。结果:在观察组的80例手足口病患儿中,有55例患儿的乳酸脱氢酶高于正常值,异常率为68.75%;有50例患儿的肌酸激酶同工酶高于正常值,异常率为62.5%。而在对照组的30例正常儿童中,只有一例儿童的乳酸脱氢酶高于正常值,异常率为3.3%。观察组患儿心肌酶的异常率明显高于对照组儿童,二者相比差异具有显著性(P<0.05)。结论:大部分手足口病患儿都会存在心肌酶改变的情况。这种情况可导致心肌受损。因此,临床医生在对手足口病患儿进行诊治的过程中,若发现患儿出现体温升高、心率加快的症状,应及时为其做心肌酶检查,以便及时对患儿进行有效的治疗。
Objective: To analyze the changes of myocardial enzymes in children with hand-foot-mouth disease. Methods: The clinical data of 80 HFMD children diagnosed and hospitalized in our hospital from September 2011 to November 2011 were retrospectively studied. The clinical data of 30 children with routine physical examination in our hospital were retrospectively analyzed. We will 80 cases of hand, foot and mouth disease in children as the observation group, 30 cases of routine physical examination in our hospital as a control group. We observed in the observation group of children hospitalized on the day or the next day to carry out the enzyme test of myocardial enzymes, the control group of children during routine physical examination for myocardial enzyme test. Results: Of 80 cases of hand-foot-mouth disease in the observation group, 55 cases of children with lactate dehydrogenase higher than normal, the abnormal rate was 68.75%; 50 cases of children with creatine kinase isoenzyme higher than Normal, abnormal rate was 62.5%. In the control group of 30 normal children, only one case of children lactate dehydrogenase higher than normal, the abnormal rate was 3.3%. The abnormal rate of myocardial enzyme in observation group was significantly higher than that in control group, the difference was significant (P <0.05). Conclusion: Most cases of hand, foot and mouth disease in patients with myocardial enzymes will change. This condition can lead to myocardial damage. Therefore, clinicians in the diagnosis and treatment of foot and mouth disease in children during the process, if found in children with body temperature, heart rate to speed up the symptoms should be promptly done for myocardial enzymes, in order to timely treatment of children with effective.