本文通过近５年来１５６例牙周牙髓合并症临床治疗观察，提出牙周病引起牙髓病变应以综合治疗为主，治愈率为６９．１５％，单纯根管治疗会增加失败率。而牙髓病引起牙周病变则主张单纯根管治疗，治愈率７２．７２％，提高根管治疗的成功率，是治疗牙髓病引起牙周病变的关键。牙周牙髓联合病变采用综合疗法，治愈率较前二者低，仅有４０％，应进一步改进目前的治疗方法。 This article through the clinical treatment of 156 cases of periodontal pulp complications in the past 5 years. It is suggested that the periodontal disease caused by endodontic disease should be comprehensively treated with the cure rate of 69.15%. The simple root canal treatment will increase the failure rate. The pulpontal disease caused by periodontal lesions are advocated a simple root canal therapy, the cure rate was 72.72%, improve the success rate of root canal therapy, is the treatment of pulpontal disease caused by periodontal key. Periodontal and endodontic combined lesions using integrated therapy, the cure rate is lower than the previous two, only 40%, should further improve the current treatment.