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目的:为了探讨以癫痫为首发症状的脑胶质瘤的临床特点。方法:对我院(1990 ~1996 年) 以癫痫为首发症状,病程在3 个月以上,并在我院手术切除,病理证实为脑胶质细胞瘤的37 例患者,进行回顾性分析。结果:37 例患者术后病理为星形细胞瘤Ⅰ、Ⅱ级19 例,Ⅲ、Ⅳ级8 例,少枝胶质细胞瘤8 例,少枝胶质母细胞瘤2 例。提示:低级别胶质瘤居多,有显著性差异( P< 001) 。 C T 检查多呈不规则低密度影,无强化,有时需 M R I检查才能确诊。手术全切后生存最长者8 年以上。有5 例复发而再次手术,术后病理均提示:星形细胞瘤Ⅳ级。结论:以癫痫为首发症状的脑胶质细胞瘤恶性程度低,手术全切效果好,预后好。
Objective: To investigate the clinical features of gliomas with epilepsy as the first symptom. Methods: A retrospective analysis of 37 patients with epilepsy as the first symptom in our hospital (1990 ~ 1996) with a course of more than 3 months and surgical resection in our hospital with pathologically confirmed glioma was performed. Results: The pathology of 37 cases was astrocytoma Ⅰ and Ⅱ in 19 cases, Ⅲ and Ⅳ in 8 cases, oligodendroglioma in 8 cases and juvenile glioblastoma in 2 cases. Tip: low-grade gliomas mostly, there was a significant difference (P <0 01). C T examination showed mostly irregular low density, no enhancement, sometimes M R I check to confirm. After surgery, the longest survival of those who over 8 years. There are 5 cases of recurrence and reoperation, postoperative pathology tips: astrocytoma Ⅳ level. Conclusion: Epilepsy as the first symptom of glioma has a low degree of malignancy, the effect of total surgical resection is good and the prognosis is good.