目的:探讨腰椎管退行性病变+膝骨关节炎行手术治疗的效果.方法:在2016—03至2018—04,择取本院行全膝关节置换手术的,腰椎管退行性病变合并膝骨关节炎患者总计258例(426个关节),依据确诊情况分为A组(n=70,单纯膝关节骨性关节炎)、B组(n=108,膝骨关节炎伴无表现腰椎管狭窄)、C组(n=80例,膝骨关节炎伴有反应腰椎管狭窄).分析三组患者治疗前后的HSS评分、功能评分、Cobb角、膝屈曲校正度和不良反应.结果:治疗前后三组HSS评分、功能性评分比较,差异均无统计学意义(P＞0.05);单“,”Objective: To investigate the effect of surgical treatment of lumbar degenerative diseases + knee osteoarthritis. Methods: from March 2016 to April 2018, 258 patients (426 joints) with degenerative lesions of lumbar spinal canal complicated with knee osteoarthritis were selected for total knee arthroplasty in our hospital. According to the diagnosis, they were divided into group A (n = 70, simple knee osteoarthritis), group B (n = 108, knee osteoarthritis with no lumbar spinal stenosis) and group C (n = 80 cases, knee osteoarthritis with reactive lumbar spinal stenosis). The HSS score, functional score, Cobb angle, knee flexion correction and adverse reactions of the three groups before and after treatment were analyzed. Results: there was no significant difference in HSS score and functional score among the three groups before and after treatment (P ＞ 0.05) There was no difference in knee flexion correction and Cobb angle between the single knee replacement group and the double knee replacement group (P ＞ 0.05); after treatment, the single knee replacement group was less than the double knee replacement group (P ＜ 0.05) Conclusion: total knee arthroplasty is effective for patients with lumbar degenerative diseases + knee osteoarthritis, but there may be aggravation of lumbar reaction after operation, so treatment should be carried out according to the specific situation.